Asian Journal of Applied Chemistry Research

Structural Investigation and Antibacterial Activity of Cu(II), Co(II), Ni(II) and Zn(II) Complexes of a Schiff Base Derived from Salicylaldehyde and Thiosemicarbazide

Tuly Paul

Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.

Md. Faruk Hossen

Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.

Md. Kudrat-E- Zahan

Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.

Md. Masuqul Haque

Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.

Rausan Zamir

Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.

Md. Ali Asraf *

Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.

*Author to whom correspondence should be addressed.

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Abstract

The metal (II) complexes, Na₂[ML₂] [M = Cu, Co, Ni, and Zn], of salicylaldehyde thiosemicarbazone (L) containing a trifunctional ONS-donor system have been synthesized and characterized on the basis of physicochemical data by elemental analysis, magnetic moment, molar conductance, and spectroscopic (electronic, IR and ESI-MS). The ligand functions as ONS tridentates producing octahedral complexes. All compounds showed significant antibacterial activity in different ranges against gram positive (Bacillus subtillus) and gram negative (Escherichia coli) bacteria.

Keywords: Schiff bases, thiosemicarbazone, complexation, antibacterial activity.

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