Structural Elucidation, 3D Molecular Modeling and Antibacterial Activity of Ni (II), Co (II), Cu (II) and Mn (II) Complexes Containing Salophen Ligand
Md. Ali Asraf *
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Mahbubur Rahman
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
D. C. Kabiraz
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Rezaul H. Ansary
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Faruk Hossen
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Fazlul Haque
Department of Zoology, Rajshahi University, Rajshahi-6205, Bangladesh.
C. M. Zakaria
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
The salophen ligand and its complexes of Ni(II), Co(II), Cu(II), and Mn(II) are explored in terms of synthesis, conductivity; magnetic measurements, elemental analysis, FT-IR; electronic spectra, and antibacterial activities. The 3D molecular modeling structures of the ligand and its metal complexes are obtained by using Argus lab software. The experimental data shows that the ligand is tetradentate and bonded to the metal ion via N2O2 donor atoms. Antibacterial activity of the synthesized compounds are checked against the microbes Bacillus cereus and Escherichia coli. The metal complexes exhibit antibacterial activity higher than that of the free ligand. This works contributes to the science of Schiff base compounds, in addition to stimulating the synthesis of new ligands and its complexes for the future advancement of coordination chemistry.
Keywords: Schiff base, tetradentate ligand, complexation, molecular modeling, antibacterial activity.